Notice: Function _load_textdomain_just_in_time was called incorrectly. Translation loading for the webspellchecker domain was triggered too early. This is usually an indicator for some code in the plugin or theme running too early. Translations should be loaded at the init action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /home/gulfindex35/public_html/ijpcs.net/wp-includes/functions.php on line 6131
Antituberculosis Therapy (ATT) Induced Thrombocytopenia: A Case Report – IJPCS
Articles

Antituberculosis Therapy (ATT) Induced Thrombocytopenia: A Case Report

Written by admin

International Journal of Pharmacology and Clinical Sciences, 2013, 2, 4, 126-128.
Published: December 2013
Type: Case Report
Authors: R. Dinesh Prabhu, G. Vikneswaran, Chultin Lepcha, and N. Tombi Singh

Author(s) affiliations:
R. Dinesh Prabhu1, G. Vikneswaran2*, Chultin Lepcha1, N. Tombi Singh3

1Post Graduate, Department of Respiratory Medicine, Regional Institute of Medical Sciences, Imphal , Manipur, India.
2Post Graduate, Department of Pharmacology, Regional Institute of Medical Sciences, Imphal , Manipur, India.
3Professor, Department of Respiratory Medicine, Regional Institute of Medical Sciences, Imphal , Manipur, India.

Abstract

Thrombocytopenia is a rare adverse effect seen with anti-tubercular drugs. We report an 80 year old male with tubercular right pleural effusion, on Category I Anti-tubercular therapy (ATT) for 3 weeks who presented with melena and epistaxis. On evaluation, he had thrombocytopenia which was found to be rifampicin-induced. ATT was restarted without rifampicin and there were no bleeding episodes. Though, rifampicin is well tolerated, but on rare occasions it can cause thrombocytopenia.

Keywords: ATT, Intermittent regimen, Rifampicin, Thrombocytopenia, Tuberculosis

View: DOWNLOAD PDF